腫瘤免疫治療實驗室
TUMOR IMMUNOTHERAPY LAB
Dr. Kuang-Wen Liao
The institute of Molecular Medicine and Bioengineering
College of Biological Science and Technology
National Chiao Tung University
Rm.731 303, Xian-Chi Building, No. 75, Bo’ai St., East Dist., Hsinchu City 300, Taiwan (R.O.C.)
新竹市東區博愛街75號賢齊館7F-731室(老師辦公室), 729(學生研究室), 735(共同實驗室)
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Chia-Hung Chen, Tzu-Han Weng, Cheng-Hsun Chuang, Kai-Yao Huang, Sih-Cheng Huang, Pin-Rong Chen, Hsiao-Hsuan Huang, Ling-Ya Huang, Pei-Chun Shen, Po-Ya Chuang, Hsiao-Yen Huang, Yi-Syuan Wu, Hao-Chiun Chang, Shun-Long Weng, Kuang-Wen Liao (2023, Jan). Transdermal nanolipoplex simultaneously inhibits subcutaneous melanoma growth and suppresses systemically metastatic melanoma by activating host immunity. Nanomedicine: nanotechnology biology and medicine, 47: 102628. 本 人為通訊作者.
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Hsiao-Chin Hong, Cheng-Hsun Chuang, Wei-Chih Huang, Shun-Long Weng, Chia-Hung Chen, Kuang-Hsin Chang, Kuang-Wen Liao, Hsien-Da Huang (2020, Jul). A panel of eight microRNAs is a good predictive parameter for triple-negative breast cancer relapse. Theranostics, 10(19):8771-8789. 本 人為通訊作者.
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Kai-Fu Chang, Jinghua Tsai Chang, Xiao-Fan Huang, Yu-Ling Lin, Kuang-Wen Liao, Chien-Wei Huang and Nu-Man Tsai (2020, May). Antitumor Effects of NButylidenephthalide Encapsulated in Lipopolyplexs in Colorectal Cancer Cells. Molecules, 25(10):2394.
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Yu-Wen Huang, Chih-Yang Lin, Hsiao-Chi Tsai, Yi-Chin Fong, Chien-Kuo Han, Yuan-Li Huang, Wen-Tung Wu, Shih-Ping Cheng, Hao-Chiun Chang, KuangWen Liao, Shih- Wei Wang, Chih-Hsin Tang (2020, May). Amphiregulin promotes cisplatin chemoresistance by upregulating ABCB1 expression in human chondrosarcoma. Aging,12
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Mau-Shin Chi, Minesh P. Mehta, Kai-Lin Yang, Hung-Chih Lai, Ying-Chu Lin, Hui-Ling Ko, Yu-Shan Wang, Kuang-Wen Liao and Kwan-Hwa Chi (2020, Mar). Putative Abscopal Effect in Three Patients Treated by Combined Radiotherapy and Modulated Electrohyperthermia. Frontiers in Oncology, 10:254.
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Shu-Yi Ho, Pin-Rong Chen, Chia-Hung Chen, Nu-Man Tsai, Yu-Hsin Lin, ChenSi Lin, Cheng-Hsun Chuang, Xiao-Fan Huang, Yi-Lin Chan, Yen-Ku Liu, ChenHan Chung, Shun-Long Weng & Kuang-Wen Liao (2020, Mar). Lipoplex-based targeted gene therapy for the suppression of tumours with VEGFR expression by producing anti-angiogenic molecules. Journal of Nanobiotechnology, 18(1). 本 人為通訊作者.
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Shih-Wei Wang, Chien-Hsing Lee, Ming-Shen Lin, Chih-Wen Chi, Yu-Jen Chen, Guo-Shou Wang, Kuang-Wen Liao, Li-Pin Chiu, Shu-Hui Wu, DongMing Huang, Luke Chen and Yung-Shuen Shen (2020, Feb). ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma through Mitochondrial Dysfunction and p70S6K Signaling Pathway. International Journal of Molecular Sciences, 21(5):1612.
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Chia-Yen Huang, Kuang-Wen Liao, Chih-Hung Chou, Sirjana Shrestha, ChiDung Yang, Men-Yee Chiew, Hsin-Tzu Huang, Hsiao-Chin Hong, Shih-Hung Huang, Tzu-Hao Chang and Hsien-Da Huang (2020, Jan). Pilot Study to Establish a Novel Five-Gene Biomarker Panel for Predicting Lymph Node Metastasis in Patients With Early Stage Endometrial Cancer. Frontiers in
Oncology , 9:1508. 本人為通訊作者.
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Lin YL, Huang XF, Chang KF, Liao KW, Tsai NM (2020, Jan). Encapsulated nButylidenephthalide Efficiently Crosses the Blood–Brain Barrier and Suppresses Growth of Glioblastoma. International Journal of Nanomedicine, 15:749-760.
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Yu Ling Lin , Nu Man Tsai , Chia Hung Chen , Yen Ku Liu , Chung Jen Lee , ‐ ‐ ‐ ‐ ‐ Yi Lin Chan , Yu Shan Wang , Yuan Ching Chang , Chi Hsin Lin , Tse Hung ‐ ‐ ‐ ‐ ‐ Huang , Chao Ching Wang , Kwan Hwa Chi and Kuang Wen Liao (2019, Dec). ‐ ‐ Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies. Journal of Nanobiotechnology, 17:25 . 本人為通訊作者.
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Tai HC, Lee TH, Tang CH, Chen LP, Chen WC, Lee MS, Chen PC, Lin CY, Chi CW, Chen YJ, Lai CT, Chen SS, Liao KW, Lee CH, Wang SW (2019, Apr). Phomaketide A Inhibits Lymphangiogenesis in Human Lymphatic Endothelial Cells. Marine Drugs.
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Chen WC, Wang SW, Lin CY, Tsai CH, Fong YC, Lin TY, Weng SL, Huang HD, Liao KW, Tang CH (2019, Mar). Resistin Enhances Monocyte Chemoattractant Protein-1 Production in Human Synovial Fibroblasts and Facilitates Monocyte Migration. Cellular Physiology and Biochemistry. 本人為通訊作者.
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Lin YL, Chen CH, Liu YK, Huang TH, Tsai NM, Tzou SC, Liao KW (2019, Feb). Lipo-PEG-PEI complex as an intracellular transporter for protein therapeutics. International Journal of Nanomedicine, 14 1119–1130. 本人為通訊作者.
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Lin YL, Tsai NM, Chen CH, Liu YK, Lee CJ, Chan YL, Wang YS, Chang YC, Lin CH, Huang TH, Wang CC, Chi KH, Liao KW (2019, Feb). Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non‑covalent association with anti‑tumor antibodies. Journal of Nanobiotechnology. 本人為通訊作者.
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Gao HW, Chang KF, Huang XF, Lin YL, Weng JC, Liao KW, Tsai NM (2018, Dec). Antitumor Effect of n-Butylidenephthalide Encapsulated on B16/F10 Melanoma Cells In Vitro with a Polycationic Liposome Containing PEI and Polyethylene Glycol Complex. Molecules.
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Lee CJ, Wang CC, Chen M, Chuang KH, Cheng TL, Jian TY, Wang YM, Huang TH, Liao KW, Tzou SC (2018, Oct). Development of an inflammatory tissue-selective chimeric TNF receptor. Cytokine. 本人為通訊作者.
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Chuang YC, Wu HY, Lin YL, Tzou SC, Chuang CH, Jian TY, Chen PR, Chang YC, Lin CH, Huang TH, Wang CC, Chan YL, Liao KW (2018, May). Blockade of ITGA2 Induces Apoptosis and Inhibits Cell Migration in Gastric Cancer.. Biological Procedures Online. 本人為通訊作者.
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Hsu WT, Ho SY, Jian TY, Huang HN, Lin YL, Chen CH, Lin TH, Wu MS, Wu CJ, Chan YL, Liao KW. (2018, May). Helicobacter pylori-derived heat shock protein 60 increases the induction of regulatory T-cells associated with persistent infection. Microbial Pathogenesis. 本人為通訊作者.
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Ho SY, Chang BH, Chung CH, Lin YL, Chuang CH, Hsieh PJ, Huang WC, Tsai NM, Huang SC, Liu YK, Lo YC, Liao KW (2018, Apr). Development of a computational promoter with highly efficient expression in tumors.. BMC Cancer. 本人為通訊作者.
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Chi MS, Yang KL, Chang YC, Ko HL, Lin YH, Huang SC, Huang YY, Liao KW, Kondo M, Chi KH (2018, Jan). Comparing the effectiveness of combined external beam radiation and hyperthermia versus external beam radiation alone in treating patients with painful bony metastases: a phase 3 prospective, randomized, controlled trial. International Journal of Radiation Oncology Biology Physics, 100(1), 78-87.
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Chou CH, Shrestha S, Yang CD, Chang NW, Lin YL, Liao KW, Huang WC, Sun TH, Tu SJ, Lee WH, Chiew MY, Tai CS, Wei TY, Tsai TR, Huang HT, Wang CY, Wu HY, Ho SY, Chen PR, Chuang CH, Hsieh PJ, Wu YS, Chen WL, Li MJ, Wu YC, Huang XY, Ng FL, Buddhakosai W, Huang PC, Lan KC, Huang CY, Weng SL, Cheng YN, Liang C, Hsu WL, Huang HD (2018, Jan). miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions. NUCLEIC ACIDS RESEARCH, gkx1067, https://doi.org/10.1093/nar/gkx1067.
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Yeh KT, Wu WT, Subeq YM, Niu CC, Liao KW, Chen IH, Lee RP (2017, Nov). Effects of freshwater clam extract on fracture induced inflammation at early stage. Experimental and Therapeutic Medicine, 14, 5039-5044.
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Lin CM, Lin YL, Ho SY, Chen PR, Tsai YH, Chung CH, Hwang CH, Tsai NM, Tzou SC, Ke CY, Chang J. Chan YL, Wang YS, Chi KH, Liao KW* (2017, Sep). The inhibitory effect of 7, 7 ''-dimethoxyagastisflavone on the metastasis of melanoma cells via the suppression of F-actin polymerization. Oncotarget, 8(36), 60046-60059. (Accepted). 本人為通訊作者.
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Chen CL, Chiang CY, Liao KW, Ho SY, Chang YF, Lim KH, Hsieh RK, Lin YL, Su YW (2017, Mar). cIAP-2 Expression Increases in Elderly Patients with Squamous Cell Carcinoma of the Head and Neck. International Journal of Gerontology, 11(1), 22-26.
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Lin YL, Tsai NM, Hsieh CH, Ho SY, Chang J, Wu HY, Hsu MH, Chang CC, Liao KW*, Jackson T. L. B., Mold D. E., Huang R.C.C. (2016, Nov). In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(48), E7798-E7807. 本人為通訊作者.
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